Research

Turning Genetic Knowledge Into Therapies

June 29th, 2015 by FFB Canada

Taking research from the laboratory to the clinic takes time, dedication, patience and planning, and it also requires a broad network of supporters.  Here at the Foundation Fighting Blindness, we began funding Dr. Ian MacDonald’s choroideremia research in 1985. Today we are thrilled to announce that his first clinical trial of a gene therapy for…

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Investing In The Best: Our 2015 Operating Grant Winners

June 22nd, 2015 by FFB Canada

We only invest in the best research. But, how do we choose? How do we predict which research project is the most promising hope for the future? The answer is peer review—a tried and true method that is used around the world to critically evaluate new research. Studies show that this is the best way…

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Combining Stem Cells & Gene Therapy for a ‘Smart’ Sight-Saving Treatment

June 19th, 2015 by FFB Canada

Dr. Andras Nagy is world-renowned for discovering a method to create stem cells from other cells of the body, a breakthrough which overcame a major hurdle in regenerative medicine. He is also widely recognized for his research that manipulates how cells express different molecules. In his new Foundation-funded project, he is using this expertise to…

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Discovery Opens New Strategy for Preventing Vision Loss

May 25th, 2015 by FFB Canada

Many of the Foundation’s sight-saving research projects are focused on photoreceptors. This is because photoreceptors are critically important for vision – they are needed to sense light. Many blinding eye diseases involve the gradual loss of photoreceptors. In fact, in some of these diseases it appears that ONLY photoreceptors are lost. Actually, this is one…

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New Research Beginnings: Making Ideas Into Reality

May 20th, 2015 by FFB Canada

July is a month of new beginnings. At the Foundation Fighting Blindness, July 1st marks the start of a new research year. While our nation was celebrating Canada Day, we were also celebrating the official commencement of the winning research projects from our annual grant competition. Any researcher will tell you that it’s very difficult…

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Expanding the Future of Retinal Gene Therapy

April 20th, 2015 by FFB Canada

Scientists studying blindness are attracted to the transformative potential of gene therapy because it can profoundly impact the lives of people living with vision loss. The eye is an ideal organ for gene replacement therapy because it is 1) accessible, 2) less likely to reject the new gene, 3) small in size, 4) isolated from…

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Celebrating the FFB Laboratory

March 11th, 2015 by FFB Canada

With the support of our donors, the Foundation Fighting Blindness is dedicated to strengthening vision research in Canada. As part of our nation-wide effort, we have committed over $1 million to renowned researchers at Toronto Western Hospital since 2007. Today, we’re proud to announce that this long-term support has been recognized with the unveiling of…

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How Do Stem Cells Become Photoreceptors?

February 17th, 2015 by FFB Canada

For people living with blinding eye diseases, stem cell therapies are often considered the ‘holy grail’ of potential treatments. This is because stem cells have the ability to make all of the different cells in the eye that are needed for vision. For this reason, many researchers are searching for ways to use stem cells…

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Discovery Opens Doors For New AMD Treatment

February 15th, 2015 by FFB Canada

More than a million Canadians have age-related macular degeneration (AMD), which causes them to lose the central part of their vision. In the developed world, AMD is the leading cause of blindness in people over 60. With support from the Foundation Fighting Blindness community, scientists are working to change this reality. Less than 10 years…

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