Search Results for: spark

Four Vision Research and Treatment Trends to Watch in 2018   

January 22nd, 2018 by FFB Canada

With the December 2017 announcement that the world’s first ocular gene therapy had received approval by the U. S. Food and Drug Administration (FDA), there’s no doubt that 2017 was a landmark year for gene therapy. Looking back, 2017 was a year of firsts, including the first stem cell therapy clinical trial for macular degeneration…

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First gene therapy for a blinding eye disease receives FDA approval

December 19th, 2017 by Dr. Mary Sunderland

Today we are celebrating the FDA’s pathbreaking approval of Luxturna. We have been following the development of Luxturna closely. Today’s landmark FDA approval makes Luxturna the first gene therapy approved in the US that targets a disease caused by mutations in a specific gene. The next steps involve determining the price for Luxturna, which poses…

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Top 10 Things We Learned at Vision Quest 2017

November 7th, 2017 by Dr. Mary Sunderland

Vision Quest is the FFB’s educational program series that brings trusted information about emerging sight-saving treatments to people living with vision loss. This year, Vision Quest brought together more than 860 people at 9 different events across Canada. The entire FFB staff participates in Vision Quest because it gives us the opportunity to learn directly…

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FDA Panel Votes Unanimously to Approve New Gene Therapy

October 13th, 2017 by Dr. Mary Sunderland

History was made on World Sight Day, October 12, 2017, when an FDA advisory panel voted unanimously to approve a new gene therapy, Luxturna, designed to treat inherited blinding eye diseases caused by mutations in the RPE65 gene. We have been following this story closely over the past few years and celebrating every milestone along…

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Gene Therapy Improves Vision in Landmark Clinical Trial

July 14th, 2017 by Dr. Mary Sunderland

Yesterday, a landmark publication in The Lancet, a prestigious journal, showed that gene therapy can improve vision in people living with a rare blinding eye disease. The study examined the effects of an experimental gene therapy – voretigene neparvovec – to treat an inherited blinding eye disease caused by mutations in the RPE65 gene. RPE65…

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Clinical Trial Updates: Gene Therapy

June 6th, 2017 by FFB Canada

Many experts agree that gene replacement therapy is a novel approach to treating inherited degenerative retinal diseases, especially when the disease is caused by a single gene defect (or mutation). Gene replacement therapies are sometimes described as “gene addition” or “gene augmentation” therapies because the treatment strategy involves replacing a damaged gene with a new,…

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Will Gene Therapies Win the Race to Restore Sight?

June 1st, 2017 by FFB Canada

There is a lot of optimism for the potential to treat inherited eye diseases with gene therapy. Around the world, scientists are exploring ways to fix the genetic errors that lead to gene-based diseases such as retinitis pigmentosa (RP) and Leber’s congenital amaurosis (LCA), editing or creating from scratch the genetic instructions that make sight…

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Experimental Gene Therapy Completes Critical Regulatory Step

May 26th, 2017 by FFB Canada

For a long time, gene therapy—the idea that genes could be used as a medical treatment—was just that: an idea. Last week, that idea took a leap forward towards becoming a reality when the company, Spark Therapeutics, completed a key application to the Food and Drug Administration (FDA). If successful, this application would make Spark’s…

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4 Big Predictions for Vision Research in 2017

January 10th, 2017 by Dr. Mary Sunderland

Last year was full of remarkable developments in vision science. Important discoveries in stem cell biology filled in key knowledge gaps, while advancements in gene therapy moved optogenetics from the realm of science fiction to reality (check out our top 10 discoveries from 2016). Here are four key developments to look forward to in 2017….

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Networking With A Vision Impairment

December 20th, 2016 by FFB Canada

In case you missed the second annual Foundation Fighting Blindness Young Leaders Summit, here are the highlights and our favourite (and most useful) networking tips and skills that we learned from each other. The 2016 Summit was focused on networking because networking is increasingly recognized as essential for professional success. Here are some highlights and…

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